it would depend on where you are riding. I have used the BOB and had trouble with wheel shimmer and had an accident. The load can change the centre of gravity for the bike, great in straight lines. Personally I ride around Europe on cycle paths and tracks and not off road, but have been caught out, I use a Y Frame, easiest ride on the market. I carry nothing on the bike and all in the trailer. After a while you don't notice you are pulling it. Some people say it is heavy on a hill but panniers are as well. I have built a box on mine with a cover and so there is no need for bags to keep things dry.
Hope that helps.